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Further information

TOLERANCE
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McCaughan, Geoffrey W


Publications

Impact Factor

Cites


ReferenceImpact FactorCitesQuartile
Sun J, McCaughan GW, Gallagher ND, Sheil AG, Bishop GA. Deletion of spontaneous rat liver allograft acceptance by donor irradiation. Transplantation. 1995 Aug 15;60(3):233-6. PubMed PMID: 7645034.
4.546
144
1
Benseler V, McCaughan GW, Schlitt HJ, Bishop GA, Bowen DG, Bertolino P. The liver: a special case in transplantation tolerance. Semin Liver Dis. 2007 May;27(2):194-213. Review. PubMed PMID: 17520518.
4.457
127
2
Sun J, Sheil AG, Wang C, Wang L, Rokahr K, Sharland A, Jung SE, Li L, McCaughan GW, Bishop GA. Tolerance to rat liver allografts: IV. Acceptance depends on the quantity of donor tissue and on donor leukocytes. Transplantation. 1996 Dec 27;62(12):1725-30. PubMed PMID: 8990351.
4.546
117
1
Bishop GA, Sun J, DeCruz DJ, Rokahr KL, Sedgwick JD, Sheil AG, Gallagher ND, McCaughan GW. Tolerance to rat liver allografts. III. Donor cell migration and tolerance-associated cytokine production in peripheral lymphoid tissues. J Immunol. 1996 Jun 15;156(12):4925-31. PubMed PMID: 8648143.
4.886
114
2
Sharland A, Yan Y, Wang C, Bowen DG, Sun J, Sheil AG, McCaughan GW, Bishop GA. Evidence that apoptosis of activated T cells occurs in spontaneous tolerance of liver allografts and is blocked by manipulations which break tolerance. Transplantation. 1999 Dec 15;68(11):1736-45. PubMed PMID: 10609951.
4.546
83
1
McCaughan GW, Gorrell MD, Bishop GA, Abbott CA, Shackel NA, McGuinness PH, Levy MT, Sharland AF, Bowen DG, Yu D, Slaitini L, Church WB, Napoli J. Molecular pathogenesis of liver disease: an approach to hepatic inflammation, cirrhosis and liver transplant tolerance. Immunol Rev. 2000 Apr;174:172-91. Review. PubMed PMID: 10807516.
13.939
76
1
Sun J, McCaughan GW, Matsumoto Y, Sheil AG, Gallagher ND, Bishop GA. Tolerance to rat liver allografts. I. Differences between tolerance and rejection are more marked in the B cell compared with the T cell or cytokine response. Transplantation. 1994 May 15;57(9):1349-57. PubMed PMID: 8184474.
4.546
76
1
Sharland A, Shastry S, Wang C, Rokahr K, Sun J, Sheil AG, McCaughan GW, Bishop GA. Kinetics of intragraft cytokine expression, cellular infiltration, and cell death in rejection of renal allografts compared with acceptance of liver allografts in a rat model: early activation and apoptosis is associated with liver graft acceptance. Transplantation. 1998 May 27;65(10):1370-7. PubMed PMID: 9625021.
4.546
70
1
Wang C, Sun J, Sheil AG, McCaughan GW, Bishop GA. A short course of methylprednisolone immunosuppression inhibits both rejection and spontaneous acceptance of rat liver allografts. Transplantation. 2001 Jul 15;72(1):44-51. PubMed PMID: 11468533.
4.546
50
1
Bishop GA, Wang C, Sharland AF, McCaughan G. Spontaneous acceptance of liver transplants in rodents: evidence that liver leucocytes induce recipient T-cell death by neglect. Immunol Cell Biol. 2002 Feb;80(1):93-100. Review. PubMed PMID: 11869366.
3.764
47
2
Bishop GA, McCaughan GW. Immune activation is required for the induction of liver allograft tolerance: implications for immunosuppressive therapy. Liver Transpl. 2001 Mar;7(3):161-72. Review. PubMed PMID: 11244155.
4.57
45
1
Yan Y, Shastry S, Richards C, Wang C, Bowen DG, Sharland AF, Painter DM, McCaughan GW, Bishop GA. Posttransplant administration of donor leukocytes induces long-term acceptance of kidney or liver transplants by an activation-associated immune mechanism. J Immunol. 2001 Apr 15;166(8):5258-64. PubMed PMID: 11290811.
4.886
42
2
Bishop GA, Ierino FL, Sharland AF, Hall BM, Alexander SI, Sandrin MS, Coates PT, McCaughan GW. Approaching the promise of operational tolerance in clinical transplantation. Transplantation. 2011 May 27;91(10):1065-74. doi: 10.1097/TP.0b013e318215e742. Review. PubMed PMID: 21544029.
4.546
31
1
Alex Bishop G, Bertolino PD, Bowen DG, McCaughan GW. Tolerance in liver transplantation. Best Pract Res Clin Gastroenterol. 2012 Feb;26(1):73-84. doi: 10.1016/j.bpg.2012.01.003. Review. PubMed PMID: 22482527.
3.991
27
2
Laurence JM, Wang C, Park ET, Buchanan A, Clouston A, Allen RD, Mccaughan GW, Bishop GA, Sharland AF. Blocking indoleamine dioxygenase activity early after rat liver transplantation prevents long-term survival but does not cause acute rejection. Transplantation. 2008 May 15;85(9):1357-61. doi: 10.1097/TP.0b013e31816fc27f. PubMed PMID: 18475196.
4.546
19
1
Wang C, Tay SS, Tran GT, Hodgkinson SJ, Allen RD, Hall BM, McCaughan GW, Sharland AF, Bishop GA. Donor IL-4-treatment induces alternatively activated liver macrophages and IDO-expressing NK cells and promotes rat liver allograft acceptance. Transpl Immunol. 2010 Feb;22(3-4):172-8. doi: 10.1016/j.trim.2009.11.005. Epub 2009 Nov 26. PubMed PMID: 19944758.
1.624
18
3
Wong YC, McCaughan GW, Bowen DG, Bertolino P. The CD8 T-cell response during tolerance induction in liver transplantation. Clin Transl Immunology. 2016 Oct 14;5(10):e102. eCollection 2016 Oct. Review. PubMed PMID: 27867515; PubMed Central PMCID: PMC5099425.
15
Cordoba SP, Wang C, Williams R, Li J, Smit L, Sharland A, Allen R, McCaughan G, Bishop A. Gene array analysis of a rat model of liver transplant tolerance identifies increased complement C3 and the STAT-1/IRF-1 pathway during tolerance induction. Liver Transpl. 2006 Apr;12(4):636-43. PubMed PMID: 16555329.
4.57
14
1
Wang C, Li J, Cordoba SP, McLeod DJ, Tran GT, Hodgkinson SJ, Hall BM, McCaughan GW, Bishop GA. Posttransplant interleukin-4 treatment converts rat liver allograft tolerance to rejection. Transplantation. 2005 May 15;79(9):1116-20. PubMed PMID: 15880053.
4.546
13
1
McCaughan GW. Withdrawal of immunosuppression in liver transplant recipients: is this as good as it gets? Liver Transpl. 2002 Apr;8(4):408-10. PubMed PMID: 11965588.
4.57
9
1
McCaughan GW, Bowen DG, Bertolino PJ. Induction Phase of Spontaneous Liver Transplant Tolerance. Front Immunol. 2020 Sep 11;11:1908. doi: 10.3389/fimmu.2020.01908. eCollection 2020. Review. PubMed PMID: 33013840; PubMed Central PMCID: PMC7516030.
5.085
8
1
McCaughan GW, Bowen DG, Bertolino P. Operational tolerance in liver transplantation: shall we predict or promote? Liver Transpl. 2013 Sep;19(9):933-6. doi: 10.1002/lt.23719. PubMed PMID: 23913809.
4.57
5
1
Sun J, Matsumoto Y, McCaughan GW, Gallagher ND, Sheil AG, Bishop GA. Levels of cytokine expression in rat liver allograft rejection compared to allograft tolerance. Transplant Proc. 1992 Oct;24(5):2309. PubMed PMID: 1413072.
0.784
5
4
Fallahzadeh MA, McCaughan GW, O'Leary JG. Potential missed opportunities to improve long-term liver allograft health. Liver Transpl. 2025 Aug 29. doi: 10.1097/LVT.0000000000000720. Online ahead of print. PubMed PMID: 40879500.
4.7
Holz LE, McCaughan GW, Benseler V, Bertolino P, Bowen DG. Liver tolerance and the manipulation of immune outcomes. Inflamm Allergy Drug Targets. 2008 Mar;7(1):6-18. Review. PubMed PMID: 18473895.

Data Sources

PubMed
NCBI
SemanticScholar
Web of Science
Human Phenotype ontology
KEGG
IMIB-Arrixaca

Address

Biomedical Informatics & Bioinformatics Platform
Institute for Bio-health Research of Murcia (IMIB-Arrixaca)
Carretera Buenavista s/n, 30120
El Palmar, Murcia, Spain

E-mail

Phones

+34 968885229
+34 968885239
+34 968885249

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